Year: 2014 | Month: June | Volume 3 | Issue 1
A Preliminary Clinical Evaluation of Probiotics Pediococcus Acidilactici MTCC5101 and Bacillus Coagulans MTCC492 on Young Anemic Women
Abstract:
Human intervention studies are a requisite to justify prophylactic and therapeutic effects of probiotics. A Lactic Acid Bacterial (LAB) isolate obtained from chilli pickle has been identified as Pediococcus acidilactici MTCC5101 based on 16S rRNA gene sequence. It is a bile tolerant strain which produces Pediocin CP2 with a wide antibacterial range. Present study is focused on evaluation of probiotic potential of P. acidilactici MTCC5101 and its colonization in human gastrointestinal (GI) tract. Further in a pilot scale pre-clinical trial among 30 young anemic women, role of P. acidilactici MTCC5101 along with another probiotic Bacillus coagulans MTCC492 was assessed in absorption of therapeutic iron salt in human GI tract.
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